Table 2

Unadjusted and adjusted analysis of birth weight among gastroschisis patients and Controls

Unadjusted

Adjusted


Coefficienta

95% CIb

p-value

Coefficientc

95% CIb

p-value


Gastroschisis

-350

-415, -286

<0.001

-317

-415, -218

<0.001

Gestational age (weeks)

228

213, 244

<0.001

NDc

ND

ND

Male gender

107

-39, 253

0.151

NDc

ND

ND

Multiple gestation

-241

-391, -92

0.002

NDc

ND

ND

Maternal race/ethnicity

White

Referent

Referent

African American

-250

-363, -136

<0.001

-236

-368, -104

0.001

Native American

1

-429, 431

0.996

277

-181, 735

0.235

Asian

-219

-344, -95

0.001

-178

-301, -55

0.005

Hispanic

-182

-480, 115

0.229

-178

-510, 155

0.292

Gestational diabetes

134

-53, 323

0.160

77

-106, 260

0.407

Pre-existing diabetes

628

348, 908

<0.001

689

406, 973

<0.001

Maternal smoking

-220

-313, -128

<0.001

-142

-249, -34

0.010

Maternal hypertension

-251

-372, -129

<0.001

-354

-473, -234

<0.001

Maternal illicit drug use

-378

-545, -211

<0.001

-255

-453, -58

0.012

Maternal alcohol use

-390

-603, -176

0.005

-143

-358, 71

0.189

Single mother

-234

-316, -152

<0.001

-59

-161, 42

0.250

Maternal age (years)

13

7, 18

<0.001

-2

-9, 6

0.654

Nullipara

-164

-246, -82

<0.001

-98

-192, -6

0.037

Outborn (yes = 1, no = 0)

239

141, 337

<0.001

136

42, 230

0.005

Era (1999-2007)

1

-72, 74

0.980

27

-44, 98

0.452


a Obtained by univariate regression

b CI= 95% confidence interval

c Adjusted coefficient obtained by multiple regression. Since cases and controls were perfectly matched for gestational age, gender, and multiple gestation, these variables were not included in the multiple regression analyses. All other potential covariates were included (see methods).

Payne et al. BMC Pediatrics 2011 11:90   doi:10.1186/1471-2431-11-90

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