Adjusted mean BW of gastroschisis cases (black line) and controls (gray line) by gestational age with the 95% confidence intervals represented by the error bars. The 10th and 50th centiles were obtained from published standards. BW was adjusted using the regression equation from Table 2 and included maternal race, cigarette smoking, GHP, recreational drug use, previous pregnancies and inborn status. From 33 weeks to about 38 weeks gestation, gastroschisis cases weighed progressively less than controls, changing from -148 grams to -616 grams. The percentage of BW deficit in gastroschisis cases increased from 7% at 33 weeks gestation to 18% at 38 weeks. The small number of patients available for analysis prior to 33 and after 38 weeks resulted in wide confidence intervals and potentially unreliable estimates.
Payne et al. BMC Pediatrics 2011 11:90 doi:10.1186/1471-2431-11-90