Table 7

Non-traditional treatment usage by seizure group.

Treatment

Overall

Controls

Clinical Seizures

Subclinical Seizures


Supplement treatments


Vitamin B12

24%

32%

20%

26% ns,ns


L-Carnitine/Acetyl-L-Carnitine

21%

22%

18% ns

29% ns,ns


Magnesium

20%

26%

17% ns

22% ns,ns


Coenzyme Q10

14%

16%

12% ns

15% ns,ns


Glutathione

14%

14%

12% ns

18% ns,ns


Dimethylglycine

11%

14%

9% ns

13% ns,ns


Taurine

11%

10%

10% ns

14% ns,ns


GABA

9%

12%

8% ns

9% ns,ns


5-Hydroxytryptophan

8%

11%

6%ns

9% ns,ns


L-Carnosine

6%

5%

5% ns

10%ns,ns


Drug treatments


Chelation Therapy

12%

15%

10%ns

16% ns,ns


Hyperbaric Oxygen Therapy

7%

6%

7% ns

10% ns,ns


Dietary treatments


Gluten Free Casein Free Diet

31%

41%

25%

31%ns,ns


Specific Carbohydrate Diet

6%

4%

6% ns

8% ns,ns


Atkins or Modified Atkins Diet

2%

1%

3% ns

2% ns,ns


‡p < = 0.001; †p < = 0.0001

For each treatment listed, statistical comparisons were made between the clinical seizure group and the control group (superscript after the clinical seizure percentage), the subclinical seizure group and the control group (1st superscript after the subclinical seizure percentage) and between the clinical and subclinical seizure group (2nd superscript after the subclinical seizure percentage). There are 15 treatments and 3 comparisons for each treatments resulting in 45 comparisons. The Bonferroni correction results in an alpha of 0.05/45 = 0.0011, so we have set the alpha to p < = 0.001 to be conservative.

Frye et al. BMC Pediatrics 2011 11:37   doi:10.1186/1471-2431-11-37

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