Table 4

Developmental Characteristics by Seizure Group.

Developmental Diagnosis

Control

Clinical Seizures

Subclinical Seizures


Autism Disorder

61%

73%

78% ‡,ns


PDD-NOS

22%

19% ns

16% ns,ns


Asperger Syndrome

17%

8%

6% ‡,ns


Developmental Profile

Control

Clinical Seizures

Subclinical Seizures


Regression

18%

28%

38% †,ns


Plateau

7%

4% ns

8% ns,ns


Symptoms from infancy

34%

39% ns

31% ns,ns


No early symptoms

34%

29% ns

23% ns,ns


‡p < = 0.001; †p < = 0.0001

For each characteristic listed, statistical comparisons were made between the clinical seizure group and the control group (superscript after the clinical seizure percentage), the subclinical seizure group and the control group (1st superscript after the subclinical seizure percentage) and between the clinical and subclinical seizure group (2nd superscript after the subclinical seizure percentage). Since there are 3 developmental diagnosis categories and 3 comparisons for each diagnosis category resulting in 9 comparisons. The Bonferroni correction for developmental diagnosis portion of the table results in an alpha of 0.05/9 = 0.0056, so we have set the alpha to p < = 0.001 to be conservative. Since there are 4 developmental profile categories and 3 comparisons for each developmental profile category resulting in 12 comparisons. The Bonferroni correction for the developmental profile portion of the table results in an alpha of 0.05/12 = 0.0042, so we have set the alpha to p < = 0.001 to be conservative.

Frye et al. BMC Pediatrics 2011 11:37   doi:10.1186/1471-2431-11-37

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