Table 3

Tests used to diagnose or rule-out seizures by seizure group.

Diagnostic Test

Overall

Controls

Clinical Seizures

Subclinical Seizures


Routine electroencephalogram

61.8%

28%

78%

68%†,ns


Overnight electroencephalogram

34.6%

10%

41%

60% †,†


No Test

27.5%

56%

17%

10%†,ns


Ambulatory electroencephalogram

17.6%

3%

21%

34% †,‡


Magnetoencephalography

3.4%

1%

4%ns

6% ‡,ns


Positron emission tomography

5.1%

1%

6%

10% †,ns


Single photon emission computed tomography

5.5%

1%

6%

13% †,ns


‡p < = 0.001; †p < = 0.0001

For each diagnostic test listed, statistical comparisons were made between the clinical seizure group and the control group (superscript after the clinical seizure percentage), the subclinical seizure group and the control group (1st superscript after the subclinical seizure percentage) and between the clinical and subclinical seizure group (2nd superscript after the subclinical seizure percentage). Since there are 7 diagnostic tests and 3 comparisons for each diagnostic test resulting in 21 comparisons. The Bonferroni correction results in an alpha of 0.05/21 = 0.0023, so we have set the alpha to p < = 0.001 to be conservative.

Frye et al. BMC Pediatrics 2011 11:37   doi:10.1186/1471-2431-11-37

Open Data