Table 2

WHO-recommended regimens for infants and children

Year of WHO Guideline

First-Line Regimen

Second-Line Regimen


2002

ZDV + 3TC + ABC

d4T + ddI + PI* or d4T + ddI + (EFV or NVP)


ZDV + 3TC + (NVP or EFV)

d4T + ddI + PI*


2006 Preferred

(ZDV or d4T) + 3TC + (NVP or EFV)

ddI + ABC + PI**


ABC + 3TC + (NVP or EFV)

ddI + ZDV + PI**


2006 Alternative

(ZDV or d4T) + 3TC + ABC

ddI + (EFV or NVP) +PI**


2008***

(ZDV or d4T or ABC) + 3TC + NVP


(ZDV or d4T or ABC) + 3TC + LPV/r


*PI options include LPV/r and NFV

**PI options include LPV/r, SQV/r, and NFV

***Infants <12 months of age

Waning et al. BMC Pediatrics 2010 10:74   doi:10.1186/1471-2431-10-74

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