Research article
Profile of blood cells and inflammatory mediators in periodic fever, aphthous stomatitis, pharyngitis and adenitis (PFAPA) syndrome
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* Corresponding authors: Kelly L Brown kelly.brown@gu.se - Per Wekell per.wekell@vgregion.se
- † Equal contributors
1 Department of Rheumatology and Inflammation Research, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
2 Department of Pediatrics, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
3 Department of Pediatrics, NU-Hospital Organization, Uddevalla, Sweden
4 The Queen Silvia Childrens Hospital, Gothenburg, Sweden
BMC Pediatrics 2010, 10:65 doi:10.1186/1471-2431-10-65
Published: 6 September 2010Additional files
Additional file 1:
Table S1: Clinical description of control children. A table listing age, gender, allergy and reason for hospital admission of healthy children enrolled as controls in this study.
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Additional file 2:
Figure S1: Acute phase serum proteins. The concentration of acute phase C-reactive protein (CRP, mg/L, left), serum amyloid A (SAA, mg/L, centre) and procalcitonin (μg/L, right) in sera from controls (n = 14), afebrile patients (n = 8) and patients with fever 12-18 hours (febrile, n = 6). Values are reported in Table 2. A dotted line indicates the upper and lower limits for detection for CRP and SAA or the lowest concentration of procalcitonin that may indicate an infection.
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Additional file 3:
Table S2: Complete blood count (CBC) including differential. A table listing absolute concentrations of blood cells in healthy and PFAPA children.
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Additional file 4:
Table S3: Concentration of inflammatory mediators in serum. The concentrations of 25 inflammatory mediators in sera from healthy children, PFAPA children in an afebrile interval or ࿄15 hours after fever commenced as determined my multiplex ELISA.
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