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Severe conjunctivochalasis in association with classic type Ehlers-Danlos syndrome

John K Whitaker1, Philip Alexander1, David YS Chau1 and Naing L Tint12*

Author affiliations

1 Division of Ophthalmology and Visual Sciences, Queen Medical Centre, University of Nottingham, Nottingham, NG7 2UH, UK

2 Division of Ophthalmology and Visual Science, B Floor, Eye, ENT Centre, Queens Medical Centre, Nottingham, NG7 2UH, UK

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Citation and License

BMC Ophthalmology 2012, 12:47  doi:10.1186/1471-2415-12-47

Published: 3 September 2012



Inferior conjunctivochalasis is common, but is rarely severe enough to require conjunctival excision. This report describes a patient with severe conjunctivochalasis who was subsequently diagnosed with Ehlers Danlos Syndrome, Classic Type.

Case presentation

A patient suffering from foreign body sensation, frequent blinking and bilateral inferior conjunctivochalasis was referred and treated by topical ocular lubrication. However, no improvement was observed prompting potential excision of conjunctivochalasis. Following patient consultation and clinical diagnosis including hypermobile joints and skin elasticity, poor wound healing and wide scar morphology, Ehlers-Danlos syndrome was confirmed in the patient.


This case highlights the need for direct patient questioning and provides the first reported association between conjunctiovochalasis and Ehlers-Danlos syndrome.

Conjunctivochalasis; Ehlers-Danlos syndrome; Kyphoscoliosis