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Prevalence of Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma in Upper Egypt

Tarek A Shazly12*, Abdelsattar N Farrag3, Asmaa Kamel3 and Ashraf K Al-Hussaini13

Author Affiliations

1 Department of Ophthalmology, Assiut University Hospital, One Assiut University Campus, Assiut, 71526 Egypt

2 Department of Ophthalmology, Massachusetts Eye and Ear Infirmary/Harvard Medical School, 243 Charles St, Boston, MA, 02114 USA

3 Department of Ophthalmology, Al-Hussaini Hospital, 23th July St. Assiut, 71111 Egypt

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BMC Ophthalmology 2011, 11:18  doi:10.1186/1471-2415-11-18

Published: 27 June 2011



Pseudoexfoliation (PXF) is a recognized risk factor for developing cataract, glaucoma and lens dislocation. PXF is also associated with increased risk of complications during cataract surgery due to poor mydriasis and zonular weakness. The aim of this study is to report the prevalence of pseudoexfoliation among Upper Egyptians attending the ophthalmology clinic of Assiut University Hospital.


A retrospective, chart review study conducted in the period from February 2002 to August 2009. A total of 7738 patients aged 40 years or older attending the general ophthalmic clinics were included in this study. A detailed evaluation including ophthalmic and general history, slit lamp biomicroscopy, intraocular pressure measurement, gonioscopy and dilated eye examination were performed. Patients with pseudoexfoliative material on the anterior lens surface and ⁄ or the pupillary margin in either or both eyes were labeled as having PXF.


Out of the 7738 patients included, three hundred twenty (4.14%) subjects had PXF. Mean age of PXF group was 68.15 years (SD 8.16, range 40-92 years). PXF was bilateral in 82.2% of cases. It was significantly associated with cataract, glaucoma and hearing loss. Of the PXF patients, 65% had cataract, 30.3% had glaucoma and 8.1% had hearing loss.


Pseudoexfoliation appears to be a common disorder in older individuals in Upper Egypt.