Table 4

velocity P values

Sample

2D

3D

Wt 10 nM

Wt 50 nM

mAb13

mAb13 +Wt 10 nM

mAb13 Wt 50 nM


untreated

Ctrl

< 0.0001***

-

0.0023**

< 0.0001***

< 0.0001***

< 0.0001***

< 0.0001***

TA

< 0.0001***

    0.1606

    0.5286

0.0003***

< 0.0001***

< 0.0001***

< 0.0001***


Wt 10 nM

Ctrl

-

-

-

    0.2859

< 0.0001***

    0.0190*

0.0193*

TA

-

-

-

0.0114*

< 0.0001***

< 0.0001***

< 0.0001***


Wt 50 nM

Ctrl

-

-

-

-

0.0002***

    0.1075

    0.1571

TA

-

-

-

-

0.0304*

0.0247*

0.0002***


mAb13

Ctrl

-

-

-

-

-

0.0348*

0.0015**

TA

-

-

-

-

-

    0.8733

    0.1978


mAb13 + Wt 10 nM

Ctrl

-

-

-

-

-

-

    0.4986

TA

-

-

-

-

-

-

    0.2165


P values were obtained using Mann-Whitney test. Non-significant values are underlined while relative significance levels are designated as extremely***, very**, or significant*. Bolded data represent conditions in which differences were observed between control and tumor-associated 3D matrix induced velocity due to stated treatments.

Castell√≥-Cros et al. BMC Cancer 2009 9:94   doi:10.1186/1471-2407-9-94

Open Data