Additional file 5.

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Invasive cell motility through tumor-associated 3D ECMs under PI3K and/or beta-1 integrin inhibition. Montage of six hour time-lapse videos depicting MDA-MB-231 cells invading through tumor-associated 3D ECMs (top left) in the presence of 10 nM Wortmannin (top right), 50 ╬╝g/ml mAb13 (bottom left) or a combination of both mAb13 and 10 nM Wortmannin (bottom right).

Format: MOV Size: 18MB Download file

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Castell├│-Cros et al. BMC Cancer 2009 9:94   doi:10.1186/1471-2407-9-94