Table 2

Unclassified variants identified among fifty-four triple-negative cases:

Gene

Exon

Mutation

Designation

Mutation Type

Age of Onset

Ethnic Group


BRCA1

22

676C>A

S186Y

Missense

36

Puerto Rican

BRCA1

16

4956A>G

S1613G

Missense

40

African American

BRCA1

15

4654G>T

S1512I

Missense

36

Caucasian

BRCA1

11

1186A>G

Q356R

Missense

40

Iranian


Young et al. BMC Cancer 2009 9:86   doi:10.1186/1471-2407-9-86

Open Data