Table 2

Fishers Exact test to determine probability of overlap between differentially expressed miRNAs and differentially methylated regions in colon cancer and the regions of overlap

A

Regions with Δ miRNA transcript

Genomic regions

Regions with Δ methylation

10

2707

Regions with no Δ methylation

18

72293

p-value

2.75e-8

B

Chromosome

Location

Object

Distance (bp)

Δ Methylation

X

133131074

miR-363

X

133131505

miR-20b

X

133135052

C-DMR

3547

0.45

X

133507562

C-DMR

462

0.39

X

133508024

miR-503

X

133508504

C-DMR

480

0.42

1

98284214

miR-137

1

98291025

C-DMR

6811

0.37

15

87712252

miR-9*

15

87712252

miR-9

15

87745140

C-DMR

32888

0.39

15

87749926

C-DMR

0.37

16

65755256

C-DMR

38469

0.47

16

65793725

miR-328

2

176711496

C-DMR

11781

0.37

2

176723277

miR-10b

2

219556012

C-DMR

18599

0.53

2

219574611

miR-375

22

21495270

miR-650

22

21526783

C-DMR

31513

-0.56

6

72169975

miR-30a-5p

6

72169975

miR-30a-3p

6

72185916

C-DMR

15941

0.38

6

72187453

C-DMR

8

41637116

miR-486

8

41676418

C-DMR

39302

-0.5

Genomic regions are grouped by alternating bold font.

Sarver et al. BMC Cancer 2009 9:401   doi:10.1186/1471-2407-9-401