Table 4

Validation of selected genes in an independent set of 47 tissues by real time PCR

Fold change (± SD)1

Kruskal Wallis p-Values


Genbank Acc. No.

Gene name

LMP2 vs normal/benign

Invasive vs normal/benign

LMP2 vs normal/benign

Invasive vs normal/benign

Invasive vs LMP


NM_030651

C6orf313

0.37 ± 0.52

0.19 ± 0.49

NS, p = 0.13

p < 0.01

p < 0.05

NM_015710

GLTSCR24

0.51 ± 0.61

0.17 ± 0.22

NS, p = 0.17

p < 0.01

p < 0.01

NM_006206

PDGFRA4

0.31 ± 0.51

0.15 ± 0.22

P < 0.05

p < 0.01

NS, p = 0.13

NM_003064

SLPI

3.86 ± 1.80

5.70 ± 4.20

P < 0.05

p < 0.05

NS, p = 0.95

NM_004625

WNT7A

180.0 ± 250.0

150.0 ± 205.0

P < 0.01

p < 0.001

NS, p = 0.67


1Real time PCR results were calculated using the Pfaffl (2001) method with B2M as the reference gene. 2Low malignant potential. 3Outlier (00231) removed from analysis. 4Outliers (44286, 44428) removed from analysis.

Merritt et al. BMC Cancer 2009 9:378   doi:10.1186/1471-2407-9-378

Open Data