Raman spectra of breast cancer cells treated by the HER2 IgY-SWNT complex. A 785 nm laser diode was used for excitation at 1-25 mW through a 10× objective lens on randomly selected cells. Raman spectra of a representative cell from each sample are shown. Blue line, SK-BR-3 cell treated with the HER2 IgY-SWNT complex; red line, SK-BR-3 cell treated with SWNT alone; magenta line, untreated SK-BR-3 cell; green line, MCF-7 cell treated with the HER2 IgY-SWNT complex. The Raman signal indicated by the arrow is the characteristic G band at ~1590 cm-1. Inset shows higher resolution spectrum in the area around 1590 cm-1.
Xiao et al. BMC Cancer 2009 9:351 doi:10.1186/1471-2407-9-351