Table 7 |
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|
Multivariate adjusted relative risk (RR)* and 95% confidence intervals (CI) for the association of light physical activity during four periods of life with breast cancer tumor characteristics: 118,899 postmenopausal women in the NIH-AARP Diet and Health Study |
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|
Moderate/vigorous activity |
ER-positive †RR |
95% CI |
ER- negative RR |
95% CI |
p†† |
ER- unknown RR |
95% CI |
p§ |
Invasive RR |
95% CI |
In situ RR |
95% CI |
p£ |
|||||
|
|
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|
Ages 15-18 years |
||||||||||||||||||
|
Never/Rarely |
1.00 (ref.) |
1.00 (ref.) |
1.00 (ref.) |
1.00 (ref.) |
1.00 (ref.) |
|||||||||||||
|
<1 hour/week |
1.05 |
0.82 |
1.34 |
0.85 |
0.48 |
1.49 |
1.08 |
0.89 |
1.31 |
1.05 |
0.91 |
1.22 |
1.40 |
1.04 |
1.87 |
|||
|
1-3 hours/week |
1.10 |
0.90 |
1.34 |
1.11 |
0.73 |
1.68 |
0.96 |
0.82 |
1.13 |
1.02 |
0.91 |
1.15 |
1.20 |
0.93 |
1.53 |
|||
|
4-7 hours/week |
1.22 |
1.00 |
1.47 |
0.98 |
0.64 |
1.50 |
0.94 |
0.80 |
1.10 |
1.04 |
0.93 |
1.17 |
0.90 |
0.70 |
1.17 |
|||
|
>7 hours/week |
1.18 |
0.98 |
1.42 |
0.91 |
0.61 |
1.36 |
0.24 |
1.02 |
0.88 |
1.18 |
0.33 |
1.06 |
0.95 |
1.19 |
0.89 |
0.70 |
1.17 |
0.18 |
|
Ages 19-29 years |
||||||||||||||||||
|
Never/Rarely |
1.00 (ref.) |
1.00 (ref.) |
1.00 (ref.) |
1.00 (ref.) |
1.00 (ref.) |
|||||||||||||
|
<1 hour/week |
1.18 |
0.92 |
1.52 |
0.99 |
0.56 |
1.76 |
1.01 |
0.82 |
1.24 |
1.07 |
0.92 |
1.25 |
1.12 |
0.81 |
1.54 |
|||
|
1-3 hours/week |
1.14 |
0.92 |
1.41 |
0.90 |
0.56 |
1.44 |
0.99 |
0.84 |
1.18 |
1.04 |
0.91 |
1.18 |
1.14 |
0.87 |
1.49 |
|||
|
4-7 hours/week |
1.16 |
0.94 |
1.43 |
1.15 |
0.74 |
1.80 |
0.94 |
0.79 |
1.11 |
1.03 |
0.91 |
1.17 |
0.94 |
0.71 |
1.23 |
|||
|
>7 hours/week |
1.14 |
0.93 |
1.40 |
0.96 |
0.61 |
1.49 |
0.48 |
0.99 |
0.84 |
1.16 |
0.51 |
1.04 |
0.92 |
1.18 |
0.87 |
0.67 |
1.13 |
0.23 |
|
Ages 35-39 years |
||||||||||||||||||
|
Never/Rarely |
1.00 (ref.) |
1.00 (ref.) |
1.00 (ref.) |
1.00 (ref.) |
1.00 (ref.) |
|||||||||||||
|
<1 hour/week |
1.17 |
0.91 |
1.49 |
0.93 |
0.51 |
1.71 |
1.03 |
0.83 |
1.27 |
1.07 |
0.92 |
1.25 |
1.23 |
0.90 |
1.68 |
|||
|
1-3 hours/week |
0.99 |
0.80 |
1.23 |
1.25 |
0.77 |
2.02 |
0.95 |
0.79 |
1.13 |
0.99 |
0.86 |
1.12 |
0.99 |
0.75 |
1.30 |
|||
|
4-7 hours/week |
1.08 |
0.88 |
1.33 |
1.14 |
0.71 |
1.84 |
1.03 |
0.87 |
1.22 |
1.06 |
0.93 |
1.20 |
0.92 |
0.70 |
1.21 |
|||
|
>7 hours/week |
1.01 |
0.82 |
1.24 |
1.01 |
0.63 |
1.63 |
0.99 |
0.99 |
0.83 |
1.17 |
0.99 |
1.00 |
0.88 |
1.13 |
0.85 |
0.65 |
1.12 |
0.31 |
|
Past 10 years |
||||||||||||||||||
|
Never/Rarely |
1.00 (ref.) |
1.00 (ref.) |
1.00 (ref.) |
1.00 (ref.) |
1.00 (ref.) |
|||||||||||||
|
<1 hour/week |
1.18 |
0.97 |
1.45 |
0.60 |
0.35 |
1.03 |
1.00 |
0.84 |
1.19 |
1.04 |
0.91 |
1.18 |
1.12 |
0.85 |
1.49 |
|||
|
1-3 hours/week |
0.96 |
0.80 |
1.14 |
0.79 |
0.53 |
1.17 |
0.88 |
0.76 |
1.01 |
0.90 |
0.81 |
1.00 |
0.99 |
0.78 |
1.25 |
|||
|
4-7 hours/week |
0.98 |
0.83 |
1.17 |
0.99 |
0.68 |
1.45 |
0.87 |
0.75 |
1.01 |
0.92 |
0.83 |
1.03 |
0.90 |
0.71 |
1.14 |
|||
|
>7 hours/week |
0.77 |
0.64 |
0.92 |
0.87 |
0.58 |
1.29 |
0.58 |
0.89 |
0.77 |
1.03 |
0.56 |
0.84 |
0.75 |
0.94 |
0.85 |
0.66 |
1.08 |
0.96 |
|
|
||||||||||||||||||
|
No. cancer cases** |
1352 |
263 |
1907 |
3522 |
736 |
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|
|
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|
* Relative risks adjusted for: age (continuous); race/ethnicity (white, black, Hispanic, Asian/Pacific Islander/American Indian); education level (<12 years or high school equivalent, 12 years or high school equivalent, post-high school vocational or technical training, some college, college graduate, post-graduate); smoking status (non-smoker, former, current); alcohol intake (grams/day, quintiles adjusted for total energy intake); family history of breast cancer (no, yes); age at menarche (<13, 13-14, ≥ 15 years); age at first birth (nulliparous, <20, 20-24, 25-29, 30+ years); parity (number of children: 0, 1-2, 3 or more); age at menopause (<40, 40-44, 45-49, 50-54, ≥ 55 years); menopausal hormone use (never, ever) ** Total numbers of cancer cases may vary due to missing physical activity values. † ER: estrogen receptor. Hormone receptor status limited to invasive cancers. †† p-value for heterogeneity comparing RR for >7 hours/week of physical activity: ER-positive and ER-negative tumors. §p-value for heterogeneity comparing RR for >7 hours/week of physical activity: ER-positive, ER-negative, and ER-unknown tumors. £ p-value for heterogeneity comparing RR for >7 hours/week of physical activity: invasive and in situ tumors |
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|
Peters et al. BMC Cancer 2009 9:349 doi:10.1186/1471-2407-9-349 |
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