Open Access Highly Accessed Research article

Early detection of breast cancer: benefits and risks of supplemental breast ultrasound in asymptomatic women with mammographically dense breast tissue. A systematic review

Monika Nothacker1, Volker Duda2, Markus Hahn3, Mathias Warm4, Friedrich Degenhardt5, Helmut Madjar6, Susanne Weinbrenner7 and Ute-Susann Albert8*

Author Affiliations

1 Agency for Quality in Medicine, Berlin, Germany

2 Department of Gynecology, Gynecological Endocrinology and Oncology, University of Marburg, Marburg, Germany

3 Department of Gynecology and Obstetrics, University of Tuebingen, Tübingen, Germany

4 Department of Gynecology and Obstetrics, University of Cologne, Cologne, Germany

5 Women's hospital, Franziskus-Hospital, Bielefeld, Germany

6 German Clinic for Diagnostics, Wiesbaden, Germany

7 Agency for Quality in Medicine, Berlin, Germany

8 Department of Gynecology, Gynecological Endocrinology and Oncology, University of Marburg, Marburg, Germany

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BMC Cancer 2009, 9:335  doi:10.1186/1471-2407-9-335

Published: 20 September 2009

Additional files

Additional file 1:

Excluded reviews and individual studies. Author, year, country; contents and reasons for exclusion.

Format: DOC Size: 40KB Download file

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Additional file 2:

Evidence table of individual studies on supplemental ultrasound in breast cancer screening (Part I). Overview of individual studies with description of population, remarks to the results, conclusion and level of evidence according to the Oxford classification for diagnostic studies.

Format: DOC Size: 85KB Download file

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Open Data

Additional file 3:

Evidence table of individual studies on supplemental ultrasound in breast cancer screening (Part II). Detailed analysis of parameters for diagnostic accuracy.

Format: DOC Size: 38KB Download file

This file can be viewed with: Microsoft Word Viewer

Open Data