Table 2

Analysis of relationships between E-cadherin, Slug and GSK3β expression with β-catenin expression in IDCs.

Parameter

Total Cases (N)

E-Cad (Mem)

E-Cad (Cyto)

Slug (Nucl)

Gsk3β (Nucl)

Gsk3β (Cyto)


-

+

P

-

+

P

-

+

P

-

+

P

-

+

P


98

53

45

46

52

65

33

64

34

52

46


β-catenin (Mem.)

Positive

33

9

24

    .0001
*1

12

21

.199

16

17

    0.012
*3

19

14

0.270

19

14

0.669

Negative

65

44

21

34

31

49

16

45

20

33

32


β-catenin (Cyto.)

Positive

42

20

22

0.309

18

24

0.543

21

21

    0.005
*4

24

18

0.198

17

25

0.070

Negative

56

33

23

28

28

44

12

40

16

35

21


β-catenin (Nucl.)

Positive

47

25

22

1.000

17

30

    0.046
*2

23

24

    0.001
*5

28

19

0.292

20

27

0.068

Negative

51

28

23

29

22

42

9

36

15

32

19


Abbreviations: E-cad, E-cadherin; Cyto, Cytoplasmic; Nucl, Nuclear and Mem, Membrane.*1β-cat (Mem)-/E-cad (Mem)-: p = 0.0001; OR = 5.59 [95% C.I = 2.21-14.1]; *2β-cat (Nucl)+/E-cad (Cyto)+: p = 0.046; OR = 2.33 [95% CI = 1.03-5.25]; *3β-cat (Mem)-/Slug (Nucl)+: p = 0.012; OR = 3.25 [95% CI = 1.34-7.89]; *4β-cat (Cyto)+/Slug (Nucl)+: p = 0.005; OR = 3.67 [95% C.I = 1.53-8.83]; *5β-cat (Nucl)+/Slug (Nucl)+: p = 0.001; OR = 4.87 [95% C.I = 1.94-12.21].

Prasad et al. BMC Cancer 2009 9:325   doi:10.1186/1471-2407-9-325

Open Data