Table 1

Summary of the effects of auraptene on rat mammary tumorigenesis

Group

Treatment

Incidence^a

Multiplicity^a

Median time to tumor (days)

112 days (16 weeks)

2

MNU + Teklad (control)

84.6 ± 7.2

1.92 ± 0.27

3

MNU + Aur. 200

76.9 ± 8.4

1.69 ± 0.27

4

MNU + Aur. 500

45.8 ± 10.4^b

1.21 ± 0.35^c

126 days (18 weeks)

2

MNU + Teklad (control)

80.7 ± 7.8

2.50 ± 0.34

80

3

MNU + Aur. 200

80.7 ± 7.8

2.08 ± 0.33

92

4

MNU + Aur. 500

66.7 ± 9.8

2.00 ± 0.43

119^d

^a Figures represent means ± SE. ^bStatistically significant (p ≤ 0.05) using ANOVA followed by Tukey test. ^cStatistically significant (p ≤ 0.05) using Mann-Whitney U-test. ^dStatistically significant (p ≤ 0.05) using the log-rank test.

Krishnan et al. BMC Cancer 2009 9:259   doi:10.1186/1471-2407-9-259