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A simple method for co-segregation analysis to evaluate the pathogenicity of unclassified variants; BRCA1 and BRCA2 as an example

Leila Mohammadi†, Maaike P Vreeswijk†, Rogier Oldenburg, Ans van den Ouweland, Jan C Oosterwijk, Annemarie H van der Hout, Nicoline Hoogerbrugge, Marjolijn Ligtenberg, Margreet G Ausems, Rob B van der Luijt, Charlotte J Dommering, Johan J Gille, Senno Verhoef, Frans B Hogervorst, Theo A van Os, Encarna Gómez García, Marinus J Blok, Juul T Wijnen, Quinta Helmer, Peter Devilee, Christi J van Asperen* and Hans C van Houwelingen

  • * Corresponding author: Christi J van Asperen asperen@lumc.nl

  • † Equal contributors

BMC Cancer 2009, 9:211 doi:10.1186/1471-2407-9-211

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