Table 2

Prostasin mRNA levels in normal and affected tissues.

Variable

mRNA level in normal tissue Mean (SD)

P^a

mRNA level in adenomas/carcinomas Mean (SD)

P^a

P^b

Prostasin

Healthy individuals

0.96 (0.29)

Mild/moderate

1.10 (0.38)

NS

0.62 (0.24)

NS

<0.001

Severe

1.08 (0.46)

NS

0.73 (0.50)

NS

<0.01

Carcinoma distant adjacent

0.85 (0.65)

NS

0.61 (0.60)

NS

<0.05

0.90 (0.76)

NS

<0.01

All adenomas and carcinomas

0.96 (0.61)

NS

0.62 (0.48)

<0.05

ND

PN-1

Healthy individual

0.022 (0.030)

Mild/moderate

0.015 (0.017)

NS

0.041 (0.028)

NS

<0.001

Severe

0.010 (0.003)

NS

0.033 (0.031)

NS

<0.05

Carcinoma distant adjacent

0.028 (0.027)

NS

0.063 (0.060)

<0.001

<0.001

0.025 (0.018)

NS

<0.001

The mRNA levels were normalised to β-actin mRNA levels.

NS = not significant

ND = not determined

p value for the comparison to the expression levels in healthy individuals using a one-way ANOVA and Tukey's post test for paired comparisons.

a) p value for the comparison to the expression levels in healthy individuals using a one-way ANOVA and Tukey's post test for paired comparisons.

b) p value for the comparison of the expression levels in normal and affected tissue from the same individual using a paired t-test

Selzer-Plon et al. BMC Cancer 2009 9:201   doi:10.1186/1471-2407-9-201