Table 5

Gene-gene associations of polymorphisms in TOP3A and BLM and risk of cancer (all cancer cases and all controls combined).^a

Polymorphisms

Genotype

OR

95% CI

rs12945597+rs2532105

GG+CC

1.0

-

A-+CC

1.6

1.2–2.1

GG+T-

2.0

1.3–3.1

A-+T-

2.7

1.8–4.3

rs1563634+rs2532105

AA+CC

1.0

-

G-+CC

1.9

1.1–3.2

AA+T-

2.0

0.85–4.

G-+T-

3.5

2.0–6.3

^a Statistically significant associations (p ≤ 0.05) are denoted in bold. The analyses were adjusted for age and sex.

Broberg et al. BMC Cancer 2009 9:140   doi:10.1186/1471-2407-9-140