Table 1

Correlation of clinicopathologic parameters with VEGF-C and COX-2 expressions.

VEGF-C Expression

COX-2 Expression



Factor

No. of cases

Low

High

P value

Low

High

P value


LVD

9.63 ± 5.09

12.83 ± 5.27

0.007a

9.17 ± 5.07

11.96 ± 5.32

0.012a

Age

≤ 50

40

23

17

0.944

12

28

0.383

> 50

30

17

13

12

18

Tumor size

≤ 2

28

18

10

0.324

10

18

0.837

> 2

42

22

20

14

28

Hisyological grade

G1 and G2

41

31

10

< 0.001

17

24

0.132

G3

29

9

20

7

22

Lymph node metastasis

Positive

32

13

19

0.010

6

26

0.012

Negative

38

27

11

18

20

Histology

IDS, NOS

59

32

27

0.420

19

40

0.614

Others

11

8

3

5

6

ER

Positive

54

32

22

0.511

22

32

0.037

Negative

16

8

8

2

14

PR

Positive

46

27

19

0.716

19

27

0.087

Negative

24

13

11

5

19

c-erbB-2

Positive

13

6

7

0.375

2

11

0.205

Negative

57

34

23

22

35

LVI

Positive

25

10

15

0.031

4

21

0.016

Negative

45

30

15

20

25


a Analysis by Mann-Whitney U test.

Zhang et al. BMC Cancer 2008 8:4   doi:10.1186/1471-2407-8-4

Open Data