Table 2

Summary of results.

All CMMLs

(N = 30)

All non AT-CMMLs

(N = 24)

MP-CMMLs

(N = 13)

MD-CMMLs

(N = 11)

AT-CMMLs

(N = 6)

RUNX1

alteration


Normal-like

17

16

6

10

1

7

Trisomy 8

3

2

2

0

1

3

Del20q

4

2

1

1

2

3

RAS pathway mutation

7

6

6

0

1

4

RUNX1 alteration

11

8

5

3

3

11

RUNX1 mutation

9

8

5

3

1

9

USP16-RUNX1

2

0

0

0

2

2


RAS pathway mutations include point mutations in KRAS, NRAS and PTPN11. RUNX1 alterations include RUNX1 mutations and breaks. Two cases (1 AT and 1 non-AT) are from the same patient.

Gelsi-Boyer et al. BMC Cancer 2008 8:299   doi:10.1186/1471-2407-8-299

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