Table 3 |
|||
|
Response to second line chemotherapy in patients with mucinous ovarian cancer with a recurrence free interval > 6 months compared to other histological subtypes |
|||
|
Mucinous |
Other histotypes |
p |
|
|
|
|||
|
N pts. |
20 |
388 |
|
|
|
|||
|
Type of second line chemotherapy |
19 |
384 |
|
|
Platinum single agent |
(8) 42.1% |
(67) 17.4% |
0.0259* |
|
Platinum based combination |
(6) 31.6% |
(184) 47.9% |
|
|
No platinum |
(5) 26.3% |
(133) 34.6% |
|
|
|
|||
|
Response rate to second line |
|||
|
All evaluable patients |
11 |
340 |
|
|
CR + PR |
(4) 36.4% |
(213) 62.6% |
0.0407* |
|
|
|||
|
Platinum |
7 |
227 |
|
|
CR + PR |
(4) 57.1% |
(170) 74.9% |
n.s.* |
|
|
|||
|
Non-platinum |
4 |
113 |
|
|
CR + PR |
(-) 0% |
(43) 38.1% |
n.s.* |
|
|
|||
|
Number of chemotherapy lines received for recurrence |
|||
|
Mean (± s.d.) |
1.9 ± 1.1 |
2.8 + 1.3 |
0.0023** |
|
|
|||
|
* χ2; **t-test |
|||
|
Pignata et al. BMC Cancer 2008 8:252 doi:10.1186/1471-2407-8-252 |
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