Figure 4.

The concentration-time curve of honokiol in plasma both liposomal honokiol and free honokiol. Mice were i.v. treated by liposomal or free honokiol at a dose of 25 mg/kg, as described in Materials and Methods. The honokiol in plasma was detected as described in Materials and Methods. Liposomal honokiol (open circle), free honokiol (solid circle).