Effects of COX-2 inhibition on production of VEGF (solid bar) and IL-8 (open bar) in NSCLC cell lines (A) A549, (B) H460 and (C) MOR/P. Lung cancer cells were treated with various concentrations (0, 0.02, 0.2, 2 and 20 μM) of NS-398 for 48 h. Each bar is the mean ± SEM of three determinations from two independent experiments. * P < 0.05.
Zhu et al. BMC Cancer 2008 8:218 doi:10.1186/1471-2407-8-218