Figure 4.

Correlation between decreased PTEN mRNA levels and amplification at the PIK3CA locus: Relative PTEN mRNA levels as determined by qRT-PCR are plotted along the X-axis and PIK3CA MIP copy number results are plotted along the Y-axis for high grade serous ovarian tumors with BRCA1 mutations (open circles) and high grade serous ovarian tumors with epigenetic loss of BRCA1 (filled triangles). MIP copy number values over 3.0 indicate amplification.

Press et al. BMC Cancer 2008 8:17   doi:10.1186/1471-2407-8-17
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