Table 3

Mutations status of the new EOC cell lines

Gene tested

TOV112D

TOV-1946

OV-1946

TOV-2223G


Somatic


TP53

EX5-36 G>A, R175H

EX8+35 C>T, R273C

EX8+35 C>T, R273C

EX4+62 G>A, W53X

KRAS

-

-

-

-

BRAF

-

-

-

-

Microsatellite Instablility (MSI)

-

-

-

-


Germline


BRCA1

-

-

-

-

BRCA2

-

-

-

-


- = no mutations were found

Ouellet et al. BMC Cancer 2008 8:152   doi:10.1186/1471-2407-8-152

Open Data