Figure 4.

Enrichment of Mono- and Oligonucleosomes after introduction of TFIIS siRNA. MCF7, PL45, A549 and MCF10A cells were treated with 5 nM TFIIS #2 siRNA and S-siRNA. Mono- and oligonucleosome values were normalized to cells treated with S-siRNA, so that a value of one represents a lack of apoptosis. Assays were performed for 72 hours.