Table 5

Outcomes of the brain metastases from breast cancer treatment according to treatment modality, number of patients, median survival and prognostic factors by other researches.

Authors

Patients(n)

Treatment

Median OS(mo)

Prognostic factors (univarate analysis)

Firlik et al. (21),2000

58

SRS

13

---

Pieper et al.(22),1997

63

Surgery+- WBRT

16

Age, menopausal status, postoperative RT, KPS, systemic disease

Wronski et al. (23), 1996.

70

Surgery+- WBRT

14

Positive estrogen receptor, meningeal carcinomatosis

Lentzsch et al. (24), 1999

145

WBRT

6.1

KPS, dose of RT, No. of BM, grade of primary

Mizutani et al. (19), 2001

113

WBRT

4.0

KPS, No. of BM, systemic metastases without bony metastasis

Fokstuen et al. (20), 2000

99

WBRT

5.0

No. of BM, systemic metastases

Mahmoud-Ahmed et al. (25) 2002

116

WBRT

4.1

KPS, WBRT dose, RPA class

Present study. 2006

174

Surgery +WBRT or WBRT

6.4

KPS, RPA, single BM, resection of lesion, extracranial metastase, control primary tumor, BS-BM system

Viani et al. BMC Cancer 2007 7:53   doi:10.1186/1471-2407-7-53