BMC Cancer

official impact factor 3.15

Open Access Highly Access Research article

Lymphatic vessel density and function in experimental bladder cancer

Marcia R Saban1*, Rheal Towner2, Nataliya Smith2, Andrew Abbott2, Michal Neeman3, Carole A Davis1, Cindy Simpson1, Julie Maier4, Sylvie Mémet5, Xue-Ru Wu6 and Ricardo Saban1

Author Affiliations

1 Department of Physiology, College of Medicine, Oklahoma University Health Sciences Center (OUHSC), Oklahoma City, OK 73104, USA

2 Small Animal MRI Core Facility, Free Radical Biology & Aging, Oklahoma Medical Research Foundation (OMRF), Oklahoma City, OK 73104, USA

3 Department of Biological Regulation, Weizmann Institute of Science, Rehovot, 76100, Israel

4 Oklahoma Medical Research Foundation (OMRF), Imaging Core Facility, Oklahoma City, Oklahoma 73104, USA

5 Unité de Mycologie Moléculaire, URA CNRS 3012, Institut Pasteur, 75724 Paris Cedex 15, France

6 Department of Urology, New York University Medical School, New York, NY 10016, USA

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BMC Cancer 2007, 7:219 doi:10.1186/1471-2407-7-219

Published: 29 November 2007

Additional files

Additional File 1:

Large lymphatics draining the lower urinary tract. Quick time movie presenting the visualization of high molecular weight dextran (500,000 MW)-Cy5.5 by NIRF injected in large collecting lymphatics draining the lower urinary tract.

Format: MOV Size: 9.3MB Download file

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Open Data

Additional File 2:

Movie obtained during pre-contrast MRI. This is a representative double echo MRI of 6-month old SV40-lacZ mouse bladder indicating the different scanning positions.

Format: MOV Size: 1.6MB Download file

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Open Data

Additional File 3:

Movie obtained post-contrast MRI. This is a representative double echo MRI obtained in the same mouse bladder represented in Figure 14 after injection of Gd-Cy5.5.

Format: MOV Size: 665KB Download file

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Open Data