Table 3

Rare allele carriage rates in subgroups of invasive breast cancer

Tumour Severity

Rare allele carriage rates (%)

Test statistic (p value)#


Tumour size

Less than 2 cm

68/414 (16.4%)

p = 0.94$

2 to 5 cm

42/270 (15.6%)

More than 5 cm

2/17 (11.8%)

Tumour Grade

Grade 1

28/149 (18.8%)

×2 = 1.99; p = 0.37

Grade 2

57/329 (17.3%)

Grade 3

33/239 (13.8%)

Nodal Invasion

Absent

82/498 (16.5%)

×2 = 0.23; p = 0.63

Present

40/219 (18.3%)

Vascular invasion

Absent

86/515 (16.7%)

×2 = 1.06; p = 0.30

Present

17/135 (12.6%)

Oestrogen Receptor Status

Present

48/264 (18.2%)

×2 = 0.91; p = 0.34

Absent

13/98 (13.3%)


# Pearson's chi-square test (with Yates correction where applicable)

$ Fisher's exact test.

Balasubramanian et al. BMC Cancer 2007 7:107   doi:10.1186/1471-2407-7-107

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