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Distribution of selected smoking characteristics for adenoma and carcinoma cases divided by APC truncation-mutation status. |
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| Cases* |
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| Adenomas |
Carcinomas |
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|
|
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| Characteristicsa |
APC+ (n = 18) |
APC- (n = 25) |
APC+ (n = 27) |
APC- (n = 57) |
|
|
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| Ever smoked |
59% (10/17) |
84% (22/26) |
68% (17/25) |
68% (37/54) |
| Mean no. cigarettes per day |
10,5 ± 5,3 |
14.5 ± 7,4 |
11,3 ± 10,0 |
13,5 ± 8,4 |
| Mean years smoking |
39,2 ± 4,6 |
30,9 ± 11,5 |
32,4 ± 15,2 |
34,2 ± 15,1 |
| Mean years since started smoking |
40,3 ± 4,8 |
38,9 ± 6,9 |
48,9 ± 6,2 |
46,3 ± 9,8 |
| Starting smoking ≥ 40 years ago |
60% (6/10) |
45% (10/22) |
100%(17/17) |
69% (25/36) |
|
*Uncertain APC truncation mutation status for one or more of the sequenced fragments gave rise to diminished numbers of CRC and adenoma cases, compared to the study population in Table 1. aNone of the smoking parameters were significantly different within the adenoma group. Within the CRC group only "starting smoking ≥ 40 years ago" yielded a significant difference, P = 0.010. | ||||
Sæbø et al. BMC Cancer 2006 6:71 doi:10.1186/1471-2407-6-71 |
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