Table 1

Characteristics of neurological toxicity during or after first-line chemotherapy with carboplatin plus paclitaxel

Neurological toxicity

No. of patients

%

A. during chemotherapy (n = 120)

No toxicity

55

(46%)

At least grade 1 toxicity

65

(54%)

Type of toxicity

Sensory, grade 1

51

(42%)

Sensory, grade 2

13

(11%)

Sensory, grade 3

1

(1%)

Motor, grade 1 (combined with sensory)

3

(3%)

B. residual toxicity after chemotherapy (n = 60 - 5 patients lost)

No toxicity at the moment of interview

46

(77%)

Time to recovery from residual neuropathy

< 2 months after the end of chemotherapy

22

37%

≥ 2 < 6 months after the end of chemotherapy

15

25%

≥ 6 months after the end of chemotherapy

9

15%

At least grade 1 residual toxicity at the moment of interview

14

(23%)

Type of residual toxicity

Sensory, grade 1

12

(20%)

Sensory, grade 2

2

(3%)

Motor, grade 1 (combined with sensory)

3

(5%)

Pignata et al. BMC Cancer 2006 6:5   doi:10.1186/1471-2407-6-5