Table 2

Distribution of C677T and A1298C genotypes by race/ethnicity1

African-American n (%)

Caucasian n (%)

p-value2

Combined n (%)


C677T

C/C

114 (81)

49 (48)

< 0.001

163 (67)

C/T

27 (19)

44 (43)

71 (29)

T/T

0

9 (9)

9 (4)


A1298C

A/A

98 (69)

37 (36)

< 0.001

135 (56)

A/C

38 (27)

49 (48)

87 (36)

C/C

5 (4)

16 (16)

21 (8)


1 Only cases who were successfully genotyped for both SNPs (n = 243) are included

2 Chi-square test comparing genotype distributions between African-Americans and Caucasians

Martin et al. BMC Cancer 2006 6:257   doi:10.1186/1471-2407-6-257

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