mRNA expression of ERCC1, OGG1 and RAI in lesions. mRNA levels were normalized to the 18S mRNA level. The classification of lesions are; M/M: adenoma with mild or moderate dysplasia; S: adenomas with severe dysplasia; C: adenocarcinomas. Open squares designate the expression level in normal colonic mucosa while crossbars designate the expression in lesions. A: ERCC1, B: OGG1, C: RAI. * designate statistically significant different mRNA levels in normal colonic mucosa compared with lesions in the same persons (p < 0.05).
Sæbø et al. BMC Cancer 2006 6:208 doi:10.1186/1471-2407-6-208