(A, B) Immunoprecipitation of Met in C4-2 and PC3 with and without activation by HGF. (C) Time-dependent activation of both Erk and Akt is visible in PC3 cells but not C4-2. (D, E) Rac is activated but not cdc42 upon HGF stimulation in C4-2 cells, as seen by immunoprecipitation of active GTPases.
Tate et al. BMC Cancer 2006 6:197 doi:10.1186/1471-2407-6-197