Table 7

Probable frequencies of the common haplotypes in the interleukin-1 gene cluster in breast cancer and screening control cohorts.

Haplotype*

Frequency

Case, Control Ratios

Chi-square

P value


GCCT

0.330

471.5 : 938.5, 321.5 : 674.5

0.352

0.5529

TTCT

0.165

220.7 : 1189.3, 176.8 : 819.2

1.865

0.1720

GCTC

0.133

182.1 : 1227.9, 138.3 : 857.7

0.469

0.4934

GCTT

0.112

169.0 : 1241.0, 99.9 : 896.1

2.239

0.1346

GCCC

0.099

145.8 : 1264.2, 91.3 : 904.7

0.913

0.3392

TCCT

0.032

42.1 : 1367.9, 35.4 : 960.6

0.602

0.4376

TCTT

0.026

32.4 : 1377.6, 30.1 : 965.9

1.202

0.2729

GTCT

0.024

36.1 : 1373.9, 22.6 : 973.4

0.214

0.6440

TTCC

0.022

33.5 : 1376.5, 19.9 : 976.1

0.377

0.5394

TTTT

0.017

21.2 : 1388.8, 19.8 : 976.2

0.817

0.3661

TCCC

0.016

24.6 : 1385.4, 14.1 : 981.9

0.4

0.5271

TCTC

0.013

16.7 : 1393.3, 14.3 : 981.7

0.295

0.5873


* The haplotypes represent the four polymorphisms (IL1A +4845G>T, IL1B +3954C>T, IL1B -511C>T and IL1RN +2018T>C) in that order.

Balasubramanian et al. BMC Cancer 2006 6:188   doi:10.1186/1471-2407-6-188

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