Table 4

Reproductive history and related endogenous exposures

Exposure*
Cases n
Controls n
OR (95% CI)

Age at menarche
< 12
22
44
Referent
12 – 14
100
212
0.9 (0.5 – 1.7)
> 14
21
30
1.2 (0.6 – 2.7)
Number of live births
None
18
58
Referent
1
22
28
2.0 (0.9 – 4.6)
≥ 2
103
200
1.4 (0.7 – 2.6)
Age at first birth
< 20
25
44
Referent
20 – 29
86
159
1.2 (0.6 – 2.4)
≥ 30
14
25
1.2 (0.4 – 3.8)
Ever Breast Feeding
No
57
75
Referent
Yes
71
154
0.7 (0.4 – 1.0)
Menstrual status on reference date**
Menstruating
21
72
Referent
Post-menopausal and not using HRT
38
58
2.8 (1.1 – 7.1)
Menstrual status 10 years before reference date**
Menstruating
35
83
Referent
Post-menopausal and not using HRT
23
46
0.6 (0.2 – 1.9)

* Reported exposure before reference date, which for a case and her two matched controls was the date the case had surgery for her meningioma.

† Odds ratio (OR) and 95% confidence intervals (CI) estimated from multivariable conditional logistic regression including continuous age and three categories of education (high school or less, some college or trade school, and college graduate or graduate school) as confounding variables. None of the tests for linear trend was significant.

** Odds ratio (OR) and 95% confidence intervals (CI) estimated from multivariable unconditional logistic regression including continuous age and three categories of education (high school or less, some college or trade school, and college graduate or graduate school) as confounding variables.

Custer et al. BMC Cancer 2006 6:152   doi:10.1186/1471-2407-6-152