Table 4

Reproductive history and related endogenous exposures

Exposure*

Cases n

Controls n

OR (95% CI)


Age at menarche

< 12

22

44

Referent

12 – 14

100

212

0.9 (0.5 – 1.7)

> 14

21

30

1.2 (0.6 – 2.7)

Number of live births

None

18

58

Referent

1

22

28

2.0 (0.9 – 4.6)

≥ 2

103

200

1.4 (0.7 – 2.6)

Age at first birth

< 20

25

44

Referent

20 – 29

86

159

1.2 (0.6 – 2.4)

≥ 30

14

25

1.2 (0.4 – 3.8)

Ever Breast Feeding

No

57

75

Referent

Yes

71

154

0.7 (0.4 – 1.0)

Menstrual status on reference date**

Menstruating

21

72

Referent

Post-menopausal and not using HRT

38

58

2.8 (1.1 – 7.1)

Menstrual status 10 years before reference date**

Menstruating

35

83

Referent

Post-menopausal and not using HRT

23

46

0.6 (0.2 – 1.9)


* Reported exposure before reference date, which for a case and her two matched controls was the date the case had surgery for her meningioma.

† Odds ratio (OR) and 95% confidence intervals (CI) estimated from multivariable conditional logistic regression including continuous age and three categories of education (high school or less, some college or trade school, and college graduate or graduate school) as confounding variables. None of the tests for linear trend was significant.

** Odds ratio (OR) and 95% confidence intervals (CI) estimated from multivariable

    unconditional
logistic regression including continuous age and three categories of education (high school or less, some college or trade school, and college graduate or graduate school) as confounding variables.

Custer et al. BMC Cancer 2006 6:152   doi:10.1186/1471-2407-6-152

Open Data