Table 2

Association between oral contraceptive use and intracranial meningioma in women

Exposure*

Cases n

Controls n

OR (95% CI)


Oral contraception (O C)

Never

48

103

Referent

Past

90

176

1.5 (0.8 – 2.7)

Current use on reference date

5

7

2.5 (0.5 – 12.6)

Years of OC use

Never

48

103

Referent

Up to 5 years

49

90

1.5 (0.8 – 3.0)

More than 5 years

46

93

1.4 (0.7 – 2.7)

First OC exposure relative to reference date

Never

48

103

Referent

1–9 years before

7

15

1.6 (0.3 – 7.5)

10 or more years before

88

168

1.5 (0.8 – 2.7)


* Reported exposure before reference date, which for a case and her two matched controls was the date the case had surgery for her meningioma.

† Odds ratio (OR) and 95% confidence intervals (CI) estimated from multivariable conditional logistic regression including continuous age and three categories of education (high school or less, some college or trade school, and college graduate or graduate school) as confounding variables. None of the tests for linear trend was significant.

Custer et al. BMC Cancer 2006 6:152   doi:10.1186/1471-2407-6-152

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