Effects of docetaxel on growth of subcutaneous LuCaP 23.1. LuCaP 23.1 fragments were implanted SC and animals were treated with 20 mg/kg docetaxel or placebo. Tumor volume was measured twice a week and blood was drawn weekly for determination of serum PSA levels. Mean ± SEM is plotted.A. Tumor volume: Docetaxel administration significantly decreased tumor volume compared to that of the control group. B. Serum PSA levels: Docetaxel decreased PSA levels significantly compared to those in the control animals.
Brubaker et al. BMC Cancer 2006 6:15 doi:10.1186/1471-2407-6-15