Table 5

Phenotypic characterizzation of MM-B1 and IST-Mes3 cells after orthotopic implantation in nude mice.

Cell lines


Marker

IST-Mes3

MM-B1


CEA

-

-

Calretinin

+

+

CD15 (LeuM1)

-

-

Ber-EP4

-

-

Cytokeratin 8/18

+

+

EMA

+ (membrane)

+ (membrane)

HBME-1

+

+

Podoplanin

+

+


IST-Mes3 and MM-B1 cells were injected into the pleural cavity of nude mice. At indicated times the mice were sacrificed and tumor nodules were removed and frozen for immunohistochemical analysis of mesothelioma-specific markers.

Martarelli et al. BMC Cancer 2006 6:130   doi:10.1186/1471-2407-6-130

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