Open Access Case report

Spontaneous regression of bone metastasis from renal cell carcinoma; A case report

Takahiro Nakajima1, Makoto Suzuki1, Soichiro Ando1, Tomohiko Iida1, Akinobu Araki2, Takehiko Fujisawa3 and Hideki Kimura1*

Author Affiliations

1 Division of Thoracic Diseases, Chiba Cancer Center, Japan

2 Division of Pathology, Chiba Cancer Center, Japan

3 Department of Thoracic Surgery, Graduate School of Medicine, Chiba University, Japan

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BMC Cancer 2006, 6:11  doi:10.1186/1471-2407-6-11

Published: 13 January 2006



Spontaneous regression of metastatic renal cell carcinoma is rarely observed.

Case presentation

Metastatic renal cell carcinoma was identified in a 70-year-old male using computed tomography-guided percutaneous needle biopsy. Two months after the diagnosis, a partial resection of the sternal bone was performed. Pathological examination revealed granulated tissue with bleeding and necrosis but no carcinogenic cells.


We report a pathologically identified case in which a sternal bone metastasis that was noticed two years after radical nephrectomy regressed completely and spontaneously.