|
Effects of various cDNA constructs on cell growth after transfection into neuroblastoma and other tumour cell lines. |
|||||
| Cell Line |
Gene |
day |
% decrease in number of cells +/-SD |
number of experiments |
p-value: test |
|
|
|||||
| SK-N-AS |
Empty vector (control) |
- |
3 × 8 |
||
| ENO1 |
1 |
22 +/- 8 |
3 × 8 |
< 0.001 |
|
| 2 |
21 +/- 4 |
3 × 8 |
0.004 |
||
| 3 |
13 +/- 3 |
3 × 8 |
0.04 |
||
| 4 |
27 +/- 12 |
3 × 8 |
< 10-5 |
||
| CORT |
1 |
3 +/- 7 |
1 × 8 |
> 0.05 |
|
| 2 |
-10 +/- 14 |
1 × 8 |
> 0.05 |
||
| 3 |
18 +/- 14 |
1 × 8 |
0.004 |
||
| 4 |
4 +/- 8 |
1 × 8 |
> 0.05 |
||
| DFFA |
1 |
2 +/- 8 |
1 × 8 |
> 0.05 |
|
| 2 |
6 +/- 11 |
1 × 8 |
> 0.05 |
||
| 3 |
19 +/- 12 |
1 × 8 |
0.002 |
||
| 4 |
14 +/- 6 |
1 × 8 |
< 10-6 |
||
| ICAT |
1 |
-6 +/- 10 |
1 × 8 |
0.04 |
|
| 2 |
-3 +/- 9 |
1 × 8 |
> 0.05 |
||
| 3 |
0 +/- 23 |
1 × 8 |
> 0.05 |
||
| 4 |
-2 +/- 6 |
1 × 8 |
> 0.05 |
||
| PEX14 |
1 |
1 +/- 10 |
1 × 8 |
> 0.05 |
|
| 2 |
-9 +/- 18 |
1 × 8 |
> 0.05 |
||
| 3 |
15 +/- 18 |
1 × 8 |
0.02 |
||
| 4 |
9 +/- 7 |
1 × 8 |
0.001 |
||
| PGD |
1 |
12 +/- 8 |
1 × 8 |
< 0.001 |
|
| 2 |
-1 +/- 16 |
1 × 8 |
> 0.05 |
||
| 3 |
24 +/- 15 |
1 × 8 |
< 0.001 |
||
| 4 |
11 +/- 7 |
1 × 8 |
< 10-4 |
||
| IMR32 |
ENO1 |
1 |
12 +/- 16 |
1 × 8 |
0.02 |
| 2 |
23 +/- 14 |
1 × 8 |
0.01 |
||
| 3 |
14 +/- 14 |
1 × 8 |
< 0.001 |
||
| 4 |
18 +/- 8 |
1 × 8 |
< 10-5 |
||
| 293 |
ENO1 |
1 |
15 +/- 20 |
1 × 8 |
0.03 |
| 2 |
49 +/- 29 |
1 × 8 |
0.006 |
||
| 3 |
19 +/- 10 |
1 × 8 |
< 0.001 |
||
| 4 |
46 +/- 9 |
1 × 8 |
< 10-7 |
||
Ejeskär et al. BMC Cancer 2005 5:161 doi:10.1186/1471-2407-5-161 |
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