Table 2

Effects of various cDNA constructs on cell growth after transfection into neuroblastoma and other tumour cell lines.

Cell Line
Gene
day
% decrease in number of cells +/-SD
number of experiments
p-value: test

SK-N-AS
Empty vector (control)

-
3 × 8


ENO1
1
22 +/- 8
3 × 8
< 0.001


2
21 +/- 4
3 × 8
0.004


3
13 +/- 3
3 × 8
0.04


4
27 +/- 12
3 × 8
< 10-5

CORT
1
3 +/- 7
1 × 8
> 0.05


2
-10 +/- 14
1 × 8
> 0.05


3
18 +/- 14
1 × 8
0.004


4
4 +/- 8
1 × 8
> 0.05

DFFA
1
2 +/- 8
1 × 8
> 0.05


2
6 +/- 11
1 × 8
> 0.05


3
19 +/- 12
1 × 8
0.002


4
14 +/- 6
1 × 8
< 10-6

ICAT
1
-6 +/- 10
1 × 8
0.04


2
-3 +/- 9
1 × 8
> 0.05


3
0 +/- 23
1 × 8
> 0.05


4
-2 +/- 6
1 × 8
> 0.05

PEX14
1
1 +/- 10
1 × 8
> 0.05


2
-9 +/- 18
1 × 8
> 0.05


3
15 +/- 18
1 × 8
0.02


4
9 +/- 7
1 × 8
0.001

PGD
1
12 +/- 8
1 × 8
< 0.001


2
-1 +/- 16
1 × 8
> 0.05


3
24 +/- 15
1 × 8
< 0.001


4
11 +/- 7
1 × 8
< 10-4
IMR32
ENO1
1
12 +/- 16
1 × 8
0.02


2
23 +/- 14
1 × 8
0.01


3
14 +/- 14
1 × 8
< 0.001


4
18 +/- 8
1 × 8
< 10-5
293
ENO1
1
15 +/- 20
1 × 8
0.03


2
49 +/- 29
1 × 8
0.006


3
19 +/- 10
1 × 8
< 0.001


4
46 +/- 9
1 × 8
< 10-7

Ejeskär et al. BMC Cancer 2005 5:161   doi:10.1186/1471-2407-5-161