Research article
Microarray analysis reveals genetic pathways modulated by tipifarnib in acute myeloid leukemia
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* Corresponding author: Mitch Raponi mraponi1@vrxus.jnj.com
1 Veridex, LLC, a Johnson and Johnson company, San Diego, CA 9212, USA
2 The Sidney Kimmel Cancer Center at Johns Hopkins, Baltimore, MD 21231, USA
3 University of Rochester Cancer Center, Rochester, NY 14642, USA
BMC Cancer 2004, 4:56 doi:10.1186/1471-2407-4-56
Published: 25 August 2004Additional files
Additional File 1:
A. Two-way hierarchical clustering of 1198 genes regulated in three AML cell lines after tipifarnib treatment. A fold-change ratio was calculated using the treated sample and its matched untreated sample. B. Gene expression changes in patient AML cells. Two-way hierarchical clustering of 1016 genes regulated in two AML patients over a three-week time course.
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Additional File 2:
A list of 141 genes with known function that were regulated in both the cell line and patient data sets.
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