Localization of MIF in human bladder – A) MIF IHC – MIF protein is localized to the urothelial cells with mostly cytoplasmic staining and some evidence of perinuclear localization. The apical surface of the urothelial cells exhibits intense immunostaining (arrows). B) MIF in situ hybridization – MIF mRNA is localized primarily to the urothelial cytoplasm.
Meyer-Siegler et al. BMC Cancer 2004 4:34 doi:10.1186/1471-2407-4-34