Research article
Medical visits for chemotherapy and chemotherapy-induced neutropenia: a survey of the impact on patient time and activities
-
* Corresponding author: Barry V Fortner bfortner@sosacorn.com
1 The West Clinic, 100 N. Humphreys Blvd., Memphis, TN 38120, USA
2 Supportive Oncology Services, Inc., 1790 Kirby Parkway, Suite 101, Memphis, TN 38138, USA
3 Supportive Oncology Services, Inc., 6903 Frying Pan Rd., Boulder, CO 80301, USA
BMC Cancer 2004, 4:22 doi:10.1186/1471-2407-4-22
Published: 20 May 2004Abstract
Background
Patients with cancer must make frequent visits to the clinic not only for chemotherapy but also for the management of treatment-related adverse effects. Neutropenia, the most common dose-limiting toxicity of myelosuppressive chemotherapy, has substantial clinical and economic consequences. Colony-stimulating factors such as filgrastim and pegfilgrastim can reduce the incidence of neutropenia, but the clinic visits for these treatments can disrupt patients' routines and activities.
Methods
We surveyed patients to assess how clinic visits for treatment with chemotherapy and the management of neutropenia affect their time and activities.
Results
The mean amounts of time affected by these visits ranged from approximately 109 hours (hospitalization for neutropenia) and 8 hours (physician and chemotherapy) to less than 3 hours (laboratory and treatment with filgrastim or pegfilgrastim). The visits for filgrastim or pegfilgrastim were comparable in length, but treatment with filgrastim requires several visits per chemotherapy cycle and treatment with pegfilgrastim requires only 1 visit.
Conclusions
This study provides useful information for future modelling of additional factors such as disease status and chemotherapy schedule and provides information that should be considered in managing chemotherapy-induced neutropenia.