Table 3

Risk of lung cancer in association with aspirin use – Roswell Park Cancer Institute, 1982–1998.

Total Sample

Females

Males




Cases

(n = 868)

Controls

(n = 935)

Adjusted OR1

(95% CI)

Cases

(n = 335)

Controls

(n = 358)

Adjusted OR1

(95% CI)

Cases

(n = 533)

Controls

(n = 577)

Adjusted OR1

(95% CI)


Non-User

747

768

1.0

299

306

1.0

448

462

1.0

Regular User2

121

167

0.57 (0.41–0.78)

36

52

0.52 (0.29–0.95)

85

115

0.62 (0.43–0.90)

1–6 tablets/week

26

41

0.53 (0.28–0.99)

9

26

0.17 (0.05–0.50)

17

15

1.01 (0.46–2.59)

7+ tablets/week

95

126

0.58 (0.41–0.82)

27

26

0.88 (0.43–1.79)

68

100

0.56 (0.37–0.83)

p = 0.04

p = 0.19

p = 0.006

1–10 years of use

90

126

0.56 (0.39–0.79)

23

38

0.42 (0.21–0.86)

67

88

0.65 (0.43–0.98)

11+ years of use

31

41

0.61 (0.34–1.09)

13

14

0.88 (0.30–2.55)

18

27

0.53 (0.26–1.10)

p = 0.06

p = 0.11

p = 0.01

1–10 tablet years3

84

106

0.63 (0.44–0.92)

20

30

0.47 (0.22–0.99)

64

76

0.73 (0.48–1.12)

11+ tablet years

37

61

0.45 (0.27–0.77)

16

22

0.61 (0.24–1.54)

21

39

0.40 (0.21–0.78)

p < 0.001

p = 0.07

p = 0.004


1 Odds ratio adjusted for age, education, and packyears of cigarettes 2 Regular use was defined as self-reported use at least once a week for at least one year 3 Tablets per day × years of use

Moysich et al. BMC Cancer 2002 2:31   doi:10.1186/1471-2407-2-31

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