Table 2

MiRNA signature associated with biologically high-grade MCTs
miRNA Fold-change p-value miRNA Fold-change p-value
Gene expression Gene expression
High vs low grade MCT High vs low grade MCT
Upregulated miRNAs
hsa-miR-301b 4.2 0.00022 hsa-miR-520b 1.8 1.8
hsa-miR-454 2.4 0.00032 hsa-miR-216b 4.6 0.023
hsa-miR-9 3.2 0.0010 hsa-miR-302b 3.2 0.024
hsa-miR-147 3.9 0.0017 hsa-miR-106b 1.6 0.026
hsa-miR-138 2.5 0.0022 hsa-miR-618 3.0 0.027
hsa-miR-330-5p 3.1 0.0027 hsa-miR-518f 3.2 0.029
hsa-miR-187 5.1 0.0029 hsa-miR-182 2.8 0.030
hsa-miR-106a 2.1 0.0044 hsa-miR-142-5p 1.7 0.031
hsa-miR-636 2.7 0.0052 hsa-miR-301a 2.8 0.032
hsa-miR-17 2.0 0.0057 hsa-miR-217 3.9 0.033
hsa-miR-449b 3.2 0.0069 hsa-miR-652 2.0 0.039
hsa-miR-130b 2.2 0.0082 hsa-miR-186 1.5 0.039
hsa-miR-192 2.5 0.0095 hsa-miR-19a 1.8 0.040
hsa-miR-448 3.1 0.010 hsa-miR-872 1.5 0.041
hsa-miR-425 3.0 0.011 hsa-miR-148b 1.8 0.043
hsa-miR-193a-3p 2.6 0.011 hsa-miR-451 2.4 0.044
hsa-miR-18b 2.2 0.014 hsa-miR-423-5p 1.7 0.048
hsa-miR-93 2.1 0.014 hsa-miR-191 1.5 0.049
hsa-miR-548b-5p 2.3 0.015 Downregulated miRNAs
hsa-miR-25 2.1 0.015 hsa-miR-885-5p -4.2 0.00011
hsa-miR-324-3p 2.3 0.017 hsa-miR-874 -5.8 0.00018
hsa-miR-326 2.6 0.017 hsa-miR-486-3p -4.6 0.00040
hsa-miR-18a 3.1 0.017 hsa-miR-299-5p -4.2 0.0020
hsa-miR-20b 2.0 0.017 hsa-miR-488 -3.9 0.0063
hsa-miR-194 2.8 0.019 hsa-miR-200a -5.5 0.034
hsa-miR-372 2.4 0.019 hsa-miR-412 -2.8 0.035

Fenger et al.

Fenger et al. BMC Cancer 2014 14:84   doi:10.1186/1471-2407-14-84

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